BDBM699513 US12110286, Example 3a

SMILES COC(=O)C(C)CCn1c2cc(Nc3cc(nc(Cl)c3C#N)C(O)=O)ccc2n(C)c1=O

InChI Key InChIKey=CLTRSZOLICYTEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 699513   

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 699513BDBM699513(US12110286, Example 3a)
Affinity DataIC50: 617nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent

TargetB-cell lymphoma 6 protein(Human)
Cancer Research Technology

US Patent
LigandChemical structure of BindingDB Monomer ID 699513BDBM699513(US12110286, Example 3a)
Affinity DataIC50: 1.18E+3nMAssay Description:Each 15 μL HTRF reaction in a 384-well black Proxiplate (Perkin Elmer) contained either 1 nM (data in table 1b) or 10 nM (data in table 1a) Trx-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2025
Entry Details
US Patent