BDBM70224 1-(3-methylcarbamoylisoquinolin-1-yl)-1,2,3,4-tetrahydroquinoline-6-carboxylic acid methylamide::US12486251, Example 58

SMILES CNC(=O)c1cc2ccccc2c(N2CCCC3=CC(C(=O)NC)CC=C32)n1

InChI Key InChIKey=BQXRAKIDHHFXQR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 70224   

TargetCREB-binding protein(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandChemical structure of BindingDB Monomer ID 70224BDBM70224(1-(3-methylcarbamoylisoquinolin-1-yl)-1,2,3,4-tetr...)
Affinity DataIC50: 100nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2026
Entry Details Article
US Patent