BDBM70225 1-(6-hydroxymethyl-3,4-dihydro-2H-quinolin-1-yl)-isoquinoline-3-carboxylic acid methylamide::US12486251, Example 59

SMILES CNC(=O)C1Cc2ccccc2C(N2CCCc3cc(CO)ccc32)=N1

InChI Key InChIKey=UAJZBIHOOROSJX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 70225   

TargetCREB-binding protein(Human)
Pharmablock Sciences (Nanjing)

US Patent
LigandChemical structure of BindingDB Monomer ID 70225BDBM70225(1-(6-hydroxymethyl-3,4-dihydro-2H-quinolin-1-yl)-i...)
Affinity DataIC50: 402nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2026
Entry Details Article
US Patent