BDBM703886 4-methyl-7-(pyridazin-3-yl)-1,5-naphthyridin-2- amine LCMS [M + 1]: 238.2. 1H NMR (400 MHz, MeOD) $#948; = 9.25 (d, J = 2.2 Hz, 1H), 9.23 (dd, J = 1.6, 5.2 Hz, 1H), 8.47 (d, J = 2.2 Hz, 1H), 8.34 (dd, J = 1.6, 8.8 Hz, 1H), 7.87 (dd, J = 5.2, 8.8 Hz, 1H), 6.99 (d, J = 1.2 Hz, 1H), 2.68 (d, J = 1.2 Hz, 3H).::US20240368153, Example 1-4

SMILES Cc1cc(N)nc2cc(-c3cccnn3)cnc12

InChI Key InChIKey=HXIPASNYKUHCAT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703886   

LigandChemical structure of BindingDB Monomer ID 703886BDBM703886(4-methyl-7-(pyridazin-3-yl)-1,5-naphthyridin-2- am...)
Affinity DataIC50: 7.46E+3nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent