BDBM703891 7-benzyl-4-methyl-1,5-naphthyridin-2-amine. LCMS [M + 1]: 250.0. 1H NMR (400 MHz, CDCl3) $#948; = 8.57 (d, J = 2.0 Hz, 1H), 7.67 (d, J = 2.0 Hz, 1H), 7.33-7.28 (m, 2H), 7.26-7.19 (m, 3H), 6.75 (d, J = 0.8 Hz, 1H), 4.72 (br s, 2H), 4.13 (s, 2H), 2.68 (d, J = 0.6 Hz, 3H).::US20240368153, Example 2-1

SMILES Cc1cc(N)nc2cc(Cc3ccccc3)cnc12

InChI Key InChIKey=BJHIVAPKSMSANE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703891   

LigandChemical structure of BindingDB Monomer ID 703891BDBM703891(7-benzyl-4-methyl-1,5-naphthyridin-2-amine. LCMS [...)
Affinity DataIC50: 6.64E+3nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2025
Entry Details
US Patent