BDBM703899 4-methyl-7-(4-pyridylmethyl)-1,5-naphthyridin-2- amine. LCMS [M + 1]: 251.3. 1H NMR (400 MHz, MeOD) $#948; = 8.48-8.42 (m, 3H), 7.67 (d, J = 2.0 Hz, 1H), 7.38-7.34 (m, 2H), 6.89 (d, J = 0.8 Hz, 1H), 4.21 (s, 2H), 2.61 (d, J = 0.8 Hz, 3H).::US20240368153, Example 2-8

SMILES Cc1cc(N)nc2cc(Cc3ccncc3)cnc12

InChI Key InChIKey=HREJNLHDTYMGAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703899   

LigandChemical structure of BindingDB Monomer ID 703899BDBM703899(4-methyl-7-(4-pyridylmethyl)-1,5-naphthyridin-2- a...)
Affinity DataIC50: 3.55E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent