BDBM703908 4-methyl-7-(pyridin-4-yloxy)-1,5-naphtbyridin-2- amine. LCMS [M + 1]: 253.2. 1H NMR (400 MHz, MeOD- d4) $#948; = 8.50 (d, J = 1.6 Hz, 1H), 8.49 (d, J = 1.6 Hz, 1H), 8.42 (d, J = 2.4 Hz, 1H), 7.55 (d, J = 2.8 Hz, 1H), 7.11 (d, J = 1.2 Hz, 1H), 7.10 (d, J = 1.6 Hz, 1H), 6.92 (d, J = 0.8 Hz, 1H), 2.65 (d, J = 1.2 Hz, 3H).::US20240368153, Example 3-8

SMILES Cc1cc(N)nc2cc(Oc3ccncc3)cnc12

InChI Key InChIKey=OFEZWBAFJBQRBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703908   

LigandChemical structure of BindingDB Monomer ID 703908BDBM703908(4-methyl-7-(pyridin-4-yloxy)-1,5-naphtbyridin-2- a...)
Affinity DataIC50: 8.40E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent