BDBM703913 4-methyl-6-(1-methylpyrazol-4-yl)-1,5- naphthyridin-2-amine. LCMS [M + 1] = 240.3. 1H NMR (400 MHz, MeOD) $#948; = 8.18 (s, 1H), 8.06 (s, 1H), 7.80-7.76 (d, J = 8.8, 1H), 7.75-7.70 (d, J = 8.8, 1H), 6.88 (s, 1H), 3.96 (s, 3H), 2.66 (s, 3H).::US20240368153, Example 4-5

SMILES Cc1cc(N)nc2ccc(-c3cnn(C)c3)nc12

InChI Key InChIKey=ZLHKROVCLZBPLZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703913   

LigandChemical structure of BindingDB Monomer ID 703913BDBM703913(4-methyl-6-(1-methylpyrazol-4-yl)-1,5- naphthyridi...)
Affinity DataIC50: 6.41E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent