BDBM703917 N2,8-dimethyl-1,5-naphthyridine-2,6- diamine. LCMS [M + 1]+:189.3. 1H NMR (400 MHz, DMSO-d6) $#948; = 7.47 (d, J = 8.8 Hz, 1H), 6.75 (d, J = 9.2 Hz, 1H), 6.65 (s, 1H), 6.50 (q, J = 4.0 Hz, 1H), 5.75 (s, 2H), 2.86 (d, J = 4.8 Hz, 3H), 2.43 (s, 3H).::US20240368153, Example 5-1

SMILES CNc1ccc2nc(N)cc(C)c2n1

InChI Key InChIKey=YQJHARXNCXOSEB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703917   

LigandChemical structure of BindingDB Monomer ID 703917BDBM703917(N2,8-dimethyl-1,5-naphthyridine-2,6- diamine. LCMS...)
Affinity DataIC50: 1.00E+5nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
3/14/2025
Entry Details
US Patent