BDBM703938 US20240368153, Example 12-3

SMILES Nc1ccc2[nH]c(NC(=O)c3ccccc3)cc2n1

InChI Key InChIKey=CFZZOSGNZOMVQC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 703938   

LigandChemical structure of BindingDB Monomer ID 703938BDBM703938(US20240368153, Example 12-3)
Affinity DataIC50: 1.83E+4nMAssay Description:Table A1: A recombinant human dual expressed Avi PRMT5/His-MEP50) protein (corresponding to amino acids for PRMT5 2-637, and 2-342 for MEP50 expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 703938BDBM703938(US20240368153, Example 12-3)
Affinity DataIC50: 9.59E+4nMAssay Description:Table B1: The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 703938BDBM703938(US20240368153, Example 12-3)
Affinity DataIC50: 9.77E+4nMAssay Description:Table B1: The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent