BDBM703964 US20240368153, Example 10-11

SMILES Cc1cc(N)nc2cc(C(=O)N(Cc3ccc(Br)cn3)[C@@H](C)c3ncccn3)cnc12

InChI Key InChIKey=LPMWBYYNVIELIY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 703964   

LigandChemical structure of BindingDB Monomer ID 703964BDBM703964(US20240368153, Example 10-11)
Affinity DataIC50: 1.04E+4nMAssay Description:Table B2: The assay uses recombinant full-length histone H2A as the PRMT5 substrate. Enzymatic transfer of the tritiated methyl group from S-adenosyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/14/2025
Entry Details
US Patent