BDBM707060 6-(2-(4-Fluorophenoxy)-2- methylpropyl)-2-thia-6- azaspiro[3.4]octane 2,2-dioxide::US20240400579, Example 132

SMILES CC(C)(CN1CCC2(C1)CS(=O)(=O)C2)Oc1ccc(F)cc1

InChI Key InChIKey=WMTPSODRJGVTQM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 707060   

LigandPNGBDBM707060(6-(2-(4-Fluorophenoxy)-2- methylpropyl)-2-thia-6- ...)
Affinity DataKi:  14.7nMAssay Description:Compounds were prepared in a 96-well U bottom plate using an Echo550 machine and 10 mM compound DMSO stock solution, followed by an 8-dose 5-fold ser...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent

TargetEmopamil-binding protein-like(Human)
Genentech

US Patent
LigandPNGBDBM707060(6-(2-(4-Fluorophenoxy)-2- methylpropyl)-2-thia-6- ...)
Affinity DataKi:  26nMAssay Description:Determination of equilibrium dissociation constant Kd of radioligand: Membrane prepared as described above was pre-incubated with PVT-WGA SPA beads (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/16/2025
Entry Details
US Patent