BDBM707583 US20240409609, Compound 121

SMILES CC(C)(O)Cn1/c(=N/C(=O)c2ccnc(Oc3cccc(O)c3C=O)c2)[nH]c2ccccc21

InChI Key InChIKey=LMDCWVVDFFFJDY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 707583   

TargetEpidermal growth factor receptor [1-18,20-1210,T790M,C797S](Human)
Terremoto Biosciences

US Patent
LigandPNGBDBM707583(US20240409609, Compound 121)
Affinity DataIC50: 7.37nMAssay Description:Biochemical activity was determined using a chelation-enhanced fluorescence assay. EGFR enzyme was incubated with DMSO-dissolved inhibitors in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor [T790M,C797S,L858R](Homo sapiens (Human))
Terremoto Biosciences

US Patent
LigandPNGBDBM707583(US20240409609, Compound 121)
Affinity DataIC50: 1.45nMAssay Description:Biochemical activity was determined using a chelation-enhanced fluorescence assay. EGFR enzyme was incubated with DMSO-dissolved inhibitors in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
US Patent

TargetEpidermal growth factor receptor(Human)
Terremoto Biosciences

US Patent
LigandPNGBDBM707583(US20240409609, Compound 121)
Affinity DataIC50: 10.5nMAssay Description:Biochemical activity was determined using a chelation-enhanced fluorescence assay. EGFR enzyme was incubated with DMSO-dissolved inhibitors in reacti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/23/2025
Entry Details
US Patent