BDBM708545 5-(3-(2-methyl-5-((3- (trifluoromethyl)phenyl) carbamoyl)phenyl)pyrrolidin- 1-yl)nicotinamide::US20240425482, Example 17

SMILES Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C1CCN(c2cncc(C(N)=O)c2)C1

InChI Key InChIKey=FAAIYMYKDJJXGP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 708545   

TargetEpithelial discoidin domain-containing receptor 1(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM708545(5-(3-(2-methyl-5-((3- (trifluoromethyl)phenyl) car...)
Affinity DataKi: <10nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent

TargetDiscoidin domain-containing receptor 2(Human)
Chiesi Farmaceutici

US Patent
LigandPNGBDBM708545(5-(3-(2-methyl-5-((3- (trifluoromethyl)phenyl) car...)
Affinity DataKi:  17.5nMAssay Description:DDR1 and DDR2 binding assays were performed using Life Technologies LanthaScreen™ Europium Kinase Binding assay. The compounds were incubated with 5 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/7/2025
Entry Details
Go to US Patent