BDBM710661 6-(((S)-2-isopropyl-4-methylpiperazin-1- yl)methyl)-2-(3-((S)-(4-methyl-4H-1,2,4- triazol-3-yl)(oxetan-3-yl)methyl)phenyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 11

SMILES CC(C)[C@H]1CN(C)CCN1Cc6cc5C(=O)N(c4cccc([C@@H](c2nncn2C)C3COC3)c4)Cc5c(C(F)F)c6

InChI Key InChIKey=JRZCPGJUGHWRQT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710661   

LigandChemical structure of BindingDB Monomer ID 710661BDBM710661(6-(((S)-2-isopropyl-4-methylpiperazin-1- yl)methyl...)
Affinity DataIC50: 5.10E+3nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710661BDBM710661(6-(((S)-2-isopropyl-4-methylpiperazin-1- yl)methyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent