BDBM710693 (S)-2-(3-(methoxy(4-methyl-4H-1,2,4- triazol-3-yl)methyl)phenyl)-6-(((1- methylcyclobutyl)amion)methyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 43

SMILES CO[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)c1nncn1C

InChI Key InChIKey=WTFSVVGAXXANBX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710693   

LigandChemical structure of BindingDB Monomer ID 710693BDBM710693((S)-2-(3-(methoxy(4-methyl-4H-1,2,4- triazol-3-yl)...)
Affinity DataIC50: 470nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710693BDBM710693((S)-2-(3-(methoxy(4-methyl-4H-1,2,4- triazol-3-yl)...)
Affinity DataIC50: 560nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent