BDBM710903 2-(3-((R)-((1s,3S)-3-(2,2- difluoroethoxy)cyclobutyl)(4-methyl-4H- 1,2,4-triazol-3-yl)methyl)phenyl)-6-(((1- methylcyclobutyl)amino)methyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 261

SMILES Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)(F)F)C2=O)c1)C1CC(OCC(F)F)C1

InChI Key InChIKey=ZMDAIGKVAJVTEG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 710903   

LigandChemical structure of BindingDB Monomer ID 710903BDBM710903(2-(3-((R)-((1s,3S)-3-(2,2- difluoroethoxy)cyclobut...)
Affinity DataIC50: 1.30E+3nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 710903BDBM710903(2-(3-((R)-((1s,3S)-3-(2,2- difluoroethoxy)cyclobut...)
Affinity DataIC50: 4.50E+3nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent