BDBM711101 4-(difluoromethyl)-2-(3-((S)-((1r,3S)-3- fluorocyclobutyl)(4-methyl-4H-1,2,4-triazol- 3-yl)methyl)phenyl)-6-(((1- methylcyclobutyl)amino)methyl)isoindolin- 1-one::US12187709, Compound 460

SMILES Cn1cnnc1[C@H](c1cccc(N2Cc3c(cc(CNC4(C)CCC4)cc3C(F)F)C2=O)c1)C1CC(F)C1

InChI Key InChIKey=SGTWKYSAVBRJTH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 711101   

LigandChemical structure of BindingDB Monomer ID 711101BDBM711101(4-(difluoromethyl)-2-(3-((S)-((1r,3S)-3- fluorocyc...)
Affinity DataIC50: 610nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 711101BDBM711101(4-(difluoromethyl)-2-(3-((S)-((1r,3S)-3- fluorocyc...)
Affinity DataIC50: 3.90E+3nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent