BDBM711106 (R)-2-(3-((4-methyl-4H-1,2,4-triazol-3- yl)(oxetan-3-yl)methyl)phenyl)-6-((((1- methylcyclopropyl)methyl)amino)methyl)- 4-(trifluoromethyl)isoindolin-1-one::US12187709, Compound 465

SMILES Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cc(CNCC4(C)CC4)cc3C(F)(F)F)C2=O)c1)C1COC1

InChI Key InChIKey=WGAXSQCSVNBPKT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 711106   

LigandChemical structure of BindingDB Monomer ID 711106BDBM711106((R)-2-(3-((4-methyl-4H-1,2,4-triazol-3- yl)(oxetan...)
Affinity DataIC50: 6.60nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 711106BDBM711106((R)-2-(3-((4-methyl-4H-1,2,4-triazol-3- yl)(oxetan...)
Affinity DataIC50: 12nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent