BDBM711113 6-(((1R,5S,6r)-3-oxabiyclo[3.1.0]hexan-6- ylamino)methyl)-2-(3-((R)-(4-methyl-4H- 1,2,4-triazol-3-yl)(oxetan-3- yl)methyl)phenyl)-4- (trifluoromethyl)isoindolin-1-one::US12187709, Compound 472

SMILES Cn1cnnc1[C@@H](c1cccc(N2Cc3c(cc(CN[C@H]4[C@@H]5CCC[C@@H]54)cc3C(F)(F)F)C2=O)c1)C1COC1

InChI Key InChIKey=WJTBOSOBJDHHEB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 711113   

LigandChemical structure of BindingDB Monomer ID 711113BDBM711113(6-(((1R,5S,6r)-3-oxabiyclo[3.1.0]hexan-6- ylamino)...)
Affinity DataIC50: 13nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 711113BDBM711113(6-(((1R,5S,6r)-3-oxabiyclo[3.1.0]hexan-6- ylamino)...)
Affinity DataIC50: 42nMAssay Description:Table 3: Compounds were 3-fold serially diluted in DMSO in a 384-well polypropylene plate (#P-05525-BC; Labcyte) to generate a source plate with 10 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/19/2025
Entry Details
US Patent