BDBM712304 US20250011311, Example 121

SMILES CC[C@H]1CN(C(=O)c2noc(-c3cc(F)c(F)c(O)c3F)n2)C[C@@H](C)O1

InChI Key InChIKey=QESVLTZORRXMMY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 712304   

Target17-beta-hydroxysteroid dehydrogenase 13(Human)
Astrazeneca

US Patent
LigandPNGBDBM712304(US20250011311, Example 121)
Affinity DataIC50: 130nMAssay Description:Final assay conditions were 80 nM of 17bHSD13, 0.5 mM of NAD, 20 μM Estradiol and various concentrations of compound in buffer (5 mM EDTA (TEKNOVA E0...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent

TargetPeroxisomal multifunctional enzyme type 2(Human)
Astrazeneca

US Patent
LigandPNGBDBM712304(US20250011311, Example 121)
Affinity DataIC50: 5.00E+4nMAssay Description:10 concentration of compounds (0.2 μl) in DMSO was added to GREINER FLUOTRAC 200 384 well plate (781076) using ECHO dispensing (BECKMAN COULTER). 80 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/22/2025
Entry Details
US Patent