BDBM716662 US20250034135, Compound 100

SMILES CC(C)c1ccccc1[C@@H]1CCCN1C1CC2(CCN(c3cc(Oc4cnc5[nH]ccc5c4)c(C(=O)NS(=O)(=O)c4cc([N+](=O)[O-])c(NC[C@H]5CC[C@](C)(O)CC5)c5ocnc45)cc3F)CC2)C1

InChI Key InChIKey=JZJWNGVFFVNHNR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716662   

TargetApoptosis regulator Bcl-2(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716662(US20250034135, Compound 100)
Affinity DataIC50: 10nMAssay Description:The detection of the binding ability between anti-apoptotic protein BCL2 and pro-apoptotic protein Bim was performed using Homogeneous Time-Resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent