BDBM716704 US20250034135, Compound 142

SMILES COc%11ccc(CN%10CCN(C8CC7(CCN(c6cc(Oc2cnc1[nH]ccc1c2)c(C(=O)NS(=O)(=O)c4cc([N+](=O)[O-])c(NC[C@@H]3CC[C@@](C)(O)CC3)c5occc45)cn6)CC7)C8)[C@H](c9ccccc9C(C)C)C%10)cc%11

InChI Key InChIKey=HCDCLEHZMPLVMU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 716704   

TargetApoptosis regulator Bcl-2(Human)
Hangzhou Healzen Therapeutics Co.

US Patent
LigandPNGBDBM716704(US20250034135, Compound 142)
Affinity DataIC50: 10nMAssay Description:The detection of the binding ability between anti-apoptotic protein BCL2 and pro-apoptotic protein Bim was performed using Homogeneous Time-Resolved ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2025
Entry Details
US Patent