BDBM717102 N-[2-chloro-4-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)-7- [(1S,6S)-5-(2-ethoxy-4-hydroxy-5-methylpyridine-3-carbonyl)-2,5- diazabicyclo[4.2.0]octan-2-yl]-6-ethyl-8-oxo-5H,8H-pyrido[2,3- b]pyrazin-5-yl]acetamide::US20250034136, Compound I-275
SMILES CCOc1ncc(C)c(O)c1C(=O)N1CCN(C2=C(CC)C(CC(=O)Nc3ccc(C(F)(F)F)cc3Cl)c3ncc(N(C)C)nc3C2=O)[C@H]2CC[C@@H]21
InChI Key InChIKey=JPFMUJADXGEUHU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 717102
TargetBifunctional 3'-5' exonuclease/ATP-dependent helicase WRN [517-1235,L1074F](Human)
Nimbus Wadjet
US Patent
Nimbus Wadjet
US Patent
Affinity DataIC50: 27.5nMAssay Description:Bovine skin gelatin (BSG), dimethyl sulfoxide (DMSO), Pluronic F-127 and tris(2-carboxyethyl)phosphine hydrochloride solution (TCEP) were purchased f...More data for this Ligand-Target Pair
