BDBM719323 US12221453, Compound I-269

SMILES [2H]C([2H])([2H])O[C@@H]1CC[C@H]1NC(=O)c1cnn2c(NC)cc(Nc3cccn(-c4ccc(C)nc4)c3=O)nc12

InChI Key InChIKey=NFDQVQBRZHAIKE-HPRDVNIFSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 719323   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM719323(US12221453, Compound I-269)
Affinity DataKd:  0.200nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMVEscan® assay (D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent