BDBM719550 3-chloro-2''-(3-(3-(difluoromethoxy)azetidine-1-carbonyl)-2-fluorophenyl)-3''-::US20250051309, Example 5.54

SMILES Cc1cnc(-c2cccc(C(=O)N3CC(OC(F)F)C3)c2F)cc1-n1c(C)cc([C@H]2C[C@@H]2c2ccc(F)cc2)c(Cl)c1=O

InChI Key InChIKey=WOQNMPVKPFWHGY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 719550   

TargetMitogen-activated protein kinase 14/1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM719550(3-chloro-2'-(3-(3-(difluoromethoxy)azetidine-1-car...)
Affinity DataIC50: 0.800nMAssay Description:In a 20 μL reaction, the compounds of various concentrations (20 nL) were pre-incubated with 0.6 nM MK2 (Abcam #ab79910) and 0.06 nM active p38α (Abc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent

LigandPNGBDBM719550(3-chloro-2'-(3-(3-(difluoromethoxy)azetidine-1-car...)
Affinity DataIC50: 32.6nMAssay Description:In a 10 μL reaction, the compounds of various concentrations (10 nL) were pre-incubated with 3 nM active p38 at (Abcam #ab271606 or in-house prepared...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/16/2025
Entry Details
US Patent