BDBM722987 US20250059220, Compound 100

SMILES O=C(Nc1ccc(Sc2ccccc2)nc1)c1ccc2sc(C(F)(F)P(=O)(O)O)c(Br)c2c1

InChI Key InChIKey=KIRONXFEQNCNNQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 722987   

TargetReceptor-type tyrosine-protein phosphatase N2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM722987(US20250059220, Compound 100)
Affinity DataIC50: 682nMAssay Description:Test compounds were dissolved in DMSO, and 10-point serial 3-fold dilution series in DMSO were prepared in Echo Qualified 384-well Polypropylene Micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM722987(US20250059220, Compound 100)
Affinity DataIC50: 540nMAssay Description:Test compounds were dissolved in DMSO, and 10-point serial 3-fold dilution series in DMSO were prepared in Echo Qualified 384-well Polypropylene Micr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/19/2025
Entry Details
US Patent