BDBM723400 US12234230, Compound 13

SMILES Cc1cc(C(=O)Nc2cccc([C@H](c3nncn3C)C3CCC3)c2)nc(C2CC2)n1

InChI Key InChIKey=LIRJTOLUYPZNAU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 723400   

TargetE3 ubiquitin-protein ligase CBL-B(Human)
Nurix Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 723400BDBM723400(US12234230, Compound 13)
Affinity DataIC50: 100nMAssay Description:Table 2: Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 54). Cbl-b displacement assays were performed in a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/24/2025
Entry Details
US Patent