BDBM725525 3-(4- ((difluoro- methyl)sulfon- amido)-3- (thiazol-2- ylmethoxy) phenyl)-5- (pyrazin-2- ylamino)- 1H-pyrazole-4- carboxamide::US20250074891, Compound 275

SMILES NC(=O)c1c(-c2ccc(NS(=O)(=O)C(F)F)c(OCc3nccs3)c2)n[nH]c1Nc1cnccn1

InChI Key InChIKey=JALQKPWOVQNBEV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 725525   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725525(3-(4- ((difluoro- methyl)sulfon- amido)-3- (thiazo...)
Affinity DataKd: <10nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725525(3-(4- ((difluoro- methyl)sulfon- amido)-3- (thiazo...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725525(3-(4- ((difluoro- methyl)sulfon- amido)-3- (thiazo...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent