BDBM726547 5-[4-[(5-fluoro-2-isopropyl-3-oxo-4H-quinoxalin-6-yl)methyl]piperazin-1-yl]-N,6-dimethyl-pyridine-2-carboxamide::US20250082630, Example 52

SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(C(C)C)c(=O)[nH]c4c3F)CC2)c(C)n1

InChI Key InChIKey=SUEUDWLKAKTAKH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 726547   

TargetPoly [ADP-ribose] polymerase 1(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726547BDBM726547(5-[4-[(5-fluoro-2-isopropyl-3-oxo-4H-quinoxalin-6-...)
Affinity DataIC50: 85nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
AstraZeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 726547BDBM726547(5-[4-[(5-fluoro-2-isopropyl-3-oxo-4H-quinoxalin-6-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent