BDBM726690 PF-07220060::US20250084095, Reference Cpd

SMILES CC(C)n1c(C(C)(C)O)nc2c(F)cc(-c3nc(N[C@@H]4CCOC[C@H]4O)ncc3Cl)cc21

InChI Key InChIKey=QYJLBHRAPDJOSO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 726690   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726690(PF-07220060 | US20250084095, Reference Cpd)
Affinity DataIC50: 8.59E+3nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726690(PF-07220060 | US20250084095, Reference Cpd)
Affinity DataIC50: 3.00E+4nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726690(PF-07220060 | US20250084095, Reference Cpd)
Affinity DataIC50: 4.37nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726690(PF-07220060 | US20250084095, Reference Cpd)
Affinity DataIC50: 76.5nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726690(PF-07220060 | US20250084095, Reference Cpd)
Affinity DataIC50: 1.88E+3nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent