BDBM727136 US20250090540, Example I-1
SMILES Cc1ccccc1Nc2c(cc(cn2)C(=O)NC)NC(=O)c3cc(cc(c3)F)C(F)(F)F
InChI Key InChIKey=ZQUWDKRQMSZGSZ-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 727136
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Relay Therapeutics
US Patent
Relay Therapeutics
US Patent
Affinity DataIC50: 750nMAssay Description:Compounds to be assayed were plated in 16 doses of 1:2 serial dilutions (20 nL volume each well) on a 1536-well plate, and the plate warmed to room t...More data for this Ligand-Target Pair

3D Structure (crystal)