BDBM728150 (Z)-1-acetyl-2-((4- (2-(1-methyl-1H- pyrazol-4-yl)phen- yl)-6-(morpholine- 4-carbonyl)quin- olin-2-yl)meth- ylene)-indolin-3- one::US20250091994, Example 196
SMILES CC(=O)n7c(=Cc5cc(c1ccccc1c2cnn(C)c2)c4cc(C(=O)N3CCOCC3)ccc4n5)c(=O)c6ccccc67
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728150
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 800nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
