BDBM728920 US20250092064, Example 107

SMILES CCOC(=O)CC(c1cc2c(c(CN3C[C@@H](CC)Oc4cccnc4[C@@H]3C)c1)OCC2)c1cc(C2CC2)c2c(nnn2C)c1C

InChI Key InChIKey=JQTWETWFPYNGTP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728920   

LigandChemical structure of BindingDB Monomer ID 728920BDBM728920(US20250092064, Example 107)
Affinity DataIC50: 20nMAssay Description:The inhibitory activity of test compounds on the binding between Nrf2 and Keap1 was determined by fluorescence polarization. A solution of 50 mM Tris...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent