BDBM7296 14-bromo-18-ethyl-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one::9-bromo-12-ethylpaullone::CHEMBL328627::NSC 704073::Paullone Analog 35

SMILES CCn1c-2c(CC(=O)Nc3ccccc-23)c2cc(Br)ccc12

InChI Key InChIKey=HEAJGTIEQPBAMJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 7296   

LigandPNGBDBM7296(CHEMBL328627 | NSC 704073 | 14-bromo-18-ethyl-8,18...)
Affinity DataIC50: 2.30E+4nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7296(CHEMBL328627 | NSC 704073 | 14-bromo-18-ethyl-8,18...)
Affinity DataIC50: 2.60E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
LigandPNGBDBM7296(CHEMBL328627 | NSC 704073 | 14-bromo-18-ethyl-8,18...)
Affinity DataIC50: 1.50E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/[gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
UniversitäT Hamburg

Curated by ChEMBL
LigandPNGBDBM7296(CHEMBL328627 | NSC 704073 | 14-bromo-18-ethyl-8,18...)
Affinity DataIC50: 2.30E+4nMAssay Description:In vitro inhibitory activity against cyclin-dependent kinase 1-cyclin B (Cyclin-Dependent Kinase) harvested from starfish oocytes.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed