BDBM732516 (S)—N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)pyrimidine-5-sulfonamide (Example 59) and (R)—N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)pyrimidine-5-sulfonamide (Example 60)::US20250115569, Example 59

SMILES CCN(C(c1ccc(F)cc1)C(F)(F)F)S(=O)(=O)c1cncnc1

InChI Key InChIKey=MQRVPFRIPFUGKB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 732516   

TargetVoltage-dependent R-type calcium channel subunit alpha-1E(Human)
Lario Therapeutics

US Patent
LigandPNGBDBM732516((S)—N-ethyl-N-(2,2,2-trifluoro-1-(4-fluorophenyl)e...)
Affinity DataIC50: 6.17E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
Go to US Patent