BDBM735506 US20250129103, Compound 93
SMILES N#CC[C@H]1CN(c2nc(OC[C@@]34CCCN3C[C@H](F)C4)nc3c(F)c(-c4cccc5ccc(F)c(F)c45)ncc23)CCN1C(=O)/C=C/CN1[C@@H]2CC[C@H]1COC2
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 735506
TargetPhosphatidylinositol 4-kinase alpha/GTPase KRas [1-169,G12C,C51S,C80L,C118S](Human)
Frontier Medicines
US Patent
Frontier Medicines
US Patent
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50S for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
TargetRAF Proto-oncogen Serine/Threonine-Protein Kinase/GTPase KRas [1-169,G12C,C51S,C80L,C118S](Human)
Frontier Medicines
US Patent
Frontier Medicines
US Patent
Affinity DataIC50: 10nMAssay Description:The AlphaScreen technology was used to determine IC50S for compound inhibition of KRAS G12C (present as the Cys-light (C51S, C80L and C118S), truncat...More data for this Ligand-Target Pair
