BDBM736433 4-((1H-pyrazol-1-yl)methyl)- 2-methoxy-N-((3-methoxy- 5,6,7,8-tetrahydronaphthalen- 2-yl)sulfonyl)benzamide::US20250136553, Compound 15

SMILES COc1cc(Cn2cccn2)ccc1C(=O)NS(=O)(=O)c1cc2c(cc1OC)CCCC2

InChI Key InChIKey=WMBLOBJTDIILBQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736433   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736433BDBM736433(4-((1H-pyrazol-1-yl)methyl)- 2-methoxy-N-((3-metho...)
Affinity DataIC50: 576nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent