BDBM736451 4-((1H-pyrazol-1-yl)methyl)- 3-methoxy-N-((2-methoxy-5- (trifluoromethyl)phenyl)sulfonyl)benzamide::US20250136553, Compound 32

SMILES COc1cc(C(=O)NS(=O)(=O)c2cc(C(F)(F)F)ccc2OC)ccc1Cn1cccn1

InChI Key InChIKey=KMJTYFZKAHRMPI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736451   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736451BDBM736451(4-((1H-pyrazol-1-yl)methyl)- 3-methoxy-N-((2-metho...)
Affinity DataIC50: 16nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent