BDBM736460 4-((1H-pyrazol-1-yl)methyl)- N-((5-fluoro-2,4- dimethoxyphenyl)sulfonyl)- 3-methoxybenzamide::US20250136553, Compound 43

SMILES COc1cc(OC)c(S(=O)(=O)NC(=O)c2ccc(Cn3cccn3)c(OC)c2)cc1F

InChI Key InChIKey=PFQMQRRICXEEEX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736460   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736460BDBM736460(4-((1H-pyrazol-1-yl)methyl)- N-((5-fluoro-2,4- dim...)
Affinity DataIC50: 18nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent