BDBM736538 5-((1H-pyrazol-1-yl)methyl)-N-(2,4- dimethoxyphenylsulfonimidoyl)-6-methoxypicolinamide::US20250136553, Compound 262

SMILES COc1ccc(S(=N)(=O)NC(=O)c2ccc(Cn3cccn3)c(OC)n2)c(OC)c1

InChI Key InChIKey=AQSWAEOQKLDMOD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736538   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736538BDBM736538(5-((1H-pyrazol-1-yl)methyl)-N-(2,4- dimethoxypheny...)
Affinity DataIC50: 115nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent