BDBM736540 5-((1H-pyrazol-1-yl)methyl)-N-((4-(tert-butyl)-2- methoxyphenyl)sulfonyl)-4-methoxypyrimidine-2-carboxamide::US20250136553, Compound 264

SMILES COc1cc(C(C)(C)C)ccc1S(=O)(=O)NC(=O)c1ncc(Cn2cccn2)c(OC)n1

InChI Key InChIKey=VXMJFQUVKNWXDI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736540   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736540BDBM736540(5-((1H-pyrazol-1-yl)methyl)-N-((4-(tert-butyl)-2- ...)
Affinity DataIC50: 12nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent