BDBM736565 (S)-5-((1H-pyrazol-1-yl)methyl)-N-(5-(1-hydroxy-2- methylpropan-2-yl)-2-methoxyphenylsulfonimidoyl)- 6-methoxypicolinamide::US20250136553, Compound 290b

SMILES COc1ccc(C(C)(C)CO)cc1[S@@](=N)(=O)NC(=O)c1ccc(Cn2cccn2)c(OC)n1

InChI Key InChIKey=KWCKOWOPGPDMKQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 736565   

TargetHistone acetyltransferase KAT6A(Human)
Olema Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 736565BDBM736565((S)-5-((1H-pyrazol-1-yl)methyl)-N-(5-(1-hydroxy-2-...)
Affinity DataIC50: 33nMAssay Description:TR-FRET based methods were used for assaying compounds of the present invention for KAT6A enzyme inhibitory activity. TR-FRET is a homogeneous proxim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2025
Entry Details
US Patent