BDBM738637 US20250145606, Example 196

SMILES CCOCc1ccc(NC(=O)c2cc(NC(=O)c3cnc(N)s3)c(C)cc2F)nc1

InChI Key InChIKey=HLHYARDBEAFRGV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 738637   

TargetMast/stem cell growth factor receptor Kit(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738637(US20250145606, Example 196)
Affinity DataIC50: 100nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738637(US20250145606, Example 196)
Affinity DataIC50: 1.00E+3nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738637(US20250145606, Example 196)
Affinity DataIC50: 1.00E+3nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738637(US20250145606, Example 196)
Affinity DataIC50: 1.00E+3nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha(Human)
Arcus Biosciences

US Patent
LigandPNGBDBM738637(US20250145606, Example 196)
Affinity DataIC50: 1.00E+3nMAssay Description:On the day of the assay, compounds were solubilized in DMSO and dispensed into a 384-well white Opti-plate (PerkinElmer, catalog #6007290) to generat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2025
Entry Details
Go to US Patent