BDBM73920 MLS001173843::SMR000596364::US11634404, Compound 65::[4-[2-(4-methoxyphenoxy)ethyl]-1-piperazinyl]-(4-methoxyphenyl)methanone::[4-[2-(4-methoxyphenoxy)ethyl]piperazin-1-yl]-(4-methoxyphenyl)methanone::[4-[2-(4-methoxyphenoxy)ethyl]piperazino]-(4-methoxyphenyl)methanone::cid_9268266
SMILES COc1ccc(OCCN2CCN(CC2)C(=O)c2ccc(OC)cc2)cc1
InChI Key InChIKey=NUWFSHWNAZZTED-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 73920
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataEC50: 710nMAssay Description:Agonist activity at human D3R expressed in CHOK1 cells assessed as induction of beta-arrestin recruitment measured after 90 mins by beta-galactosidas...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataEC50: 710nMAssay Description:Compounds were tested for their ability to compete with the orthosteric radioligand [3H]methylspiperone for binding to the D3 DAR using stable HEK ce...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataIC50: 1.40E+4nMAssay Description:For a secondary-screen and selectivity assays, DAR PathHunter βarrestin GPCR cell lines from DiscoverX (Fremont, Calif.) were used. In the D2 Re...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataIC50: 1.57E+4nMAssay Description:Antagonist activity at human D2R expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after 120 min...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataIC50: 5.00E+4nMAssay Description:For a secondary-screen and selectivity assays, DAR PathHunter βarrestin GPCR cell lines from DiscoverX (Fremont, Calif.) were used. In the D2 Re...More data for this Ligand-Target Pair
Affinity DataEC50: >7.50E+4nMAssay Description:Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
The United States of America, As Represented By The Secretary, Department of Health and Human Services
US Patent
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-methylspiperon from human D2RL expressed in HEK293 cell membranes measured after 90 mins by topcount assayMore data for this Ligand-Target Pair