BDBM743617 2-((6-((5-chloro-2-(4-(2- (4-(4-((2-(2,6- dioxopiperidin-3-yl)-1- oxoisoindolin-5-yl) ethynyl)benzyl)piperazin- 1-yl)ethoxy)piperidin- 1-yl)pyrimidin-4- yl)amino)-1-methyl-2- oxo-1,2-dihydroquinolin- 3-yl)oxy)-N- methylacetamide::US12310975, Example 119

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC(OCCN5CCN(Cc6ccc(C#Cc7ccc8c(c7)CN(C7CCC(=O)NC7=O)C8=O)cc6)CC5)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=GMJDTEUPZRVCBT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743617   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743617BDBM743617(2-((6-((5-chloro-2-(4-(2- (4-(4-((2-(2,6- dioxopip...)
Affinity DataIC50: 10nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent