BDBM743744 1-[1-({1-[5-chloro-4-({1- methyl-3- [(methylcarbamoyl) methoxy]-2-oxo-1,2- dihydroquinolin-6- yl}amino)pyrimidin-2- yl]piperidin-4- yl}methyl)piperidin-4- yl]-N-(2,6- dioxopiperidin-3-yl)-1H- 1,3-benzodiazole-4- carboxamide::US12310975, Example 283

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC(CN5CCC(n6cnc7c(C(=O)NC8CCC(=O)NC8=O)cccc76)CC5)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=IMBDAYJLQHVRHB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743744   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743744BDBM743744(1-[1-({1-[5-chloro-4-({1- methyl-3- [(methylcarbam...)
Affinity DataIC50: 100nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent