BDBM743783 2-{[1-butyl-6-({5-chloro- 2-[(3S)-3-({[2-(2,6- dioxopiperidin-3-yl)-1,3- dioxo-2,3-dihydro-1H- isoindol-4- yl]oxy}methyl)piperidin- 1-yl]pyrimidin-4- yl}amino)-2-oxo-1,2- dihydroquinolin-3- yl]oxy}-N- methylacetamide::US12310975, Example 324

SMILES CCCCn1c(=O)c(OCC(=O)NC)cc2cc(Nc3nc(N4CCC[C@H](COc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)C4)ncc3Cl)ccc21

InChI Key InChIKey=BBFLPBJNUGTJOG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743783   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743783BDBM743783(2-{[1-butyl-6-({5-chloro- 2-[(3S)-3-({[2-(2,6- dio...)
Affinity DataIC50: 10nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent