BDBM743804 4-[4-({4-[5-chloro-4-({1- methyl-3- [(methylcarbamoyl) methoxy]-2-oxo-1,2- dihydroquinolin-6- yl}amino)pyrimidin-2- yl]piperazin-1- yl}methyl)piperidin-1- yl]-N-(2,6- dioxopiperidin-3-yl)-2- propoxybenzamide::US12310975, Example 345

SMILES CCCOc1cc(N2CCC(CN3CCN(c4ncc(Cl)c(Nc5ccc6c(c5)cc(OCC(=O)NC)c(=O)n6C)n4)CC3)CC2)ccc1C(=O)NC1CCC(=O)NC1=O

InChI Key InChIKey=OETFUKKPDCIWNW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743804   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743804BDBM743804(4-[4-({4-[5-chloro-4-({1- methyl-3- [(methylcarbam...)
Affinity DataIC50: 100nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent