BDBM743808 5-{[(2S)-4-[5-chloro-4- ({3-[(methylcarbamoyl) methoxy]- 2-oxo-1-(propan-2- yl)-1,2-dihydroquinolin- 6-yl}amino)pyrimidin-2- yl]morpholin-2- yl]methoxy}-N-(2,6-::US12310975, Example 349

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCO[C@H](COc5ccc(C(=O)NC6CCC(=O)NC6=O)nc5)C4)ncc3Cl)ccc2n(C(C)C)c1=O

InChI Key InChIKey=KBBRPIVOTSKVAW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743808   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743808BDBM743808(5-{[(2S)-4-[5-chloro-4- ({3-[(methylcarbamoyl) met...)
Affinity DataIC50: 100nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent